TRIP13 Antikörper (AA 181-390)

Produktnummer ABIN7162475

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRIP13 in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TRIP13 Antikörper (AA 181-390) (ABIN7162475)

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIP13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-TRIP13 Antikörper

Bindungsspezifität: AA 181-390

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Pachytene checkpoint protein 2 homolog protein (181-390AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TRIP13

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Andere Bezeichnung: TRIP13

Hintergrund:

Background: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed:28553959).

Aliases: 16E1-BP antibody, 16E1BP antibody, Homo sapiens HPV16 E1 protein binding protein mRNA complete cds antibody, HPV16 E1 protein binding protein antibody, HPV16 E1 protein-binding protein antibody, Human papillomavirus type 16 E1 protein binding protein antibody, Human papillomavirus type 16 E1 protein-binding protein antibody, Pachytene checkpoint protein 2 homolog antibody, PCH2 antibody, Thyroid hormone receptor interactor 13 antibody, Thyroid receptor interacting protein 13 antibody, Thyroid receptor-interacting protein 13 antibody, TR-interacting protein 13 antibody, TRIP-13 antibody, Trip13 antibody, TRP13_HUMAN antibody

UniProt: Q15645