NR2C1 Antikörper (AA 1-240)
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- Target Alle NR2C1 Antikörper anzeigen
- NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
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Bindungsspezifität
- AA 1-240
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NR2C1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Nuclear receptor subfamily 2 group C member 1 protein (1-240AA)
- Isotyp
- IgG
- Top Product
- Discover our top product NR2C1 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
- Andere Bezeichnung
- NR2C1 (NR2C1 Produkte)
- Hintergrund
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Background: Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5\\\'-AGGTCA-3\\\' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
Aliases: NR2C1 antibody, TR2 antibody, Nuclear receptor subfamily 2 group C member 1 antibody, Orphan nuclear receptor TR2 antibody, Testicular receptor 2 antibody
- UniProt
- P13056
- Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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