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NR2C1 Antikörper (AA 1-240)

NR2C1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7161902
  • Target Alle NR2C1 Antikörper anzeigen
    NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-240
    Reaktivität
    • 54
    • 17
    • 11
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Human
    Wirt
    • 48
    • 8
    Kaninchen
    Klonalität
    • 52
    • 4
    Polyklonal
    Konjugat
    • 39
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NR2C1 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 19
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Nuclear receptor subfamily 2 group C member 1 protein (1-240AA)
    Isotyp
    IgG
    Top Product
    Discover our top product NR2C1 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
    Andere Bezeichnung
    NR2C1 (NR2C1 Produkte)
    Hintergrund

    Background: Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5\\\'-AGGTCA-3\\\' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.

    Aliases: NR2C1 antibody, TR2 antibody, Nuclear receptor subfamily 2 group C member 1 antibody, Orphan nuclear receptor TR2 antibody, Testicular receptor 2 antibody

    UniProt
    P13056
    Pathways
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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