NCOA6 Antikörper (AA 285-504) (FITC)

Produktnummer ABIN7161867

Der Kaninchen Polyklonal Anti-NCOA6-Antikörper wurde für validiert. Er ist geeignet, NCOA6 in Proben von Human zu detektieren.

Kurzübersicht für NCOA6 Antikörper (AA 285-504) (FITC) (ABIN7161867)

Target: NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOA6 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-NCOA6 Antikörper (FITC)

Bindungsspezifität: AA 285-504

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Nuclear receptor coactivator 6 protein (285-504AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NCOA6

Target: NCOA6 (Nuclear Receptor Coactivator 6 (NCOA6))

Andere Bezeichnung: NCOA6

Hintergrund:

Background: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.

Aliases: NCOA6 antibody, AIB3 antibody, KIAA0181 antibody, RAP250 antibody, TRBP antibody, Nuclear receptor coactivator 6 antibody, Activating signal cointegrator 2 antibody, ASC-2 antibody, Amplified in breast cancer protein 3 antibody, Cancer-amplified transcriptional coactivator ASC-2 antibody, Nuclear receptor coactivator RAP250 antibody, NRC RAP250 antibody, Nuclear receptor-activating protein antibody, 250 kDa antibody, Peroxisome proliferator-activated receptor-interacting protein antibody, PPAR-interacting protein antibody, PRIP antibody, Thyroid hormone receptor-binding protein antibody

UniProt: Q14686

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha