Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Norrie Disease (Pseudoglioma) Antikörper (AA 25-133) (HRP)

NDP Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN7161712
  • Target Alle Norrie Disease (Pseudoglioma) (NDP) Antikörper anzeigen
    Norrie Disease (Pseudoglioma) (NDP)
    Bindungsspezifität
    • 12
    • 3
    • 2
    • 1
    • 1
    AA 25-133
    Reaktivität
    • 33
    • 12
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 31
    • 3
    Kaninchen
    Klonalität
    • 33
    • 1
    Polyklonal
    Konjugat
    • 13
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser Norrie Disease (Pseudoglioma) Antikörper ist konjugiert mit HRP
    Applikation
    • 11
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Norrin protein (25-133AA)
    Isotyp
    IgG
    Top Product
    Discover our top product NDP Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Norrie Disease (Pseudoglioma) (NDP)
    Andere Bezeichnung
    NDP (NDP Produkte)
    Synonyme
    EVR2 antikoerper, FEVR antikoerper, ND antikoerper, evr2 antikoerper, fevr antikoerper, xnorrin antikoerper, Ndph antikoerper, RGD1563968 antikoerper, NDP, norrin cystine knot growth factor antikoerper, Norrie disease (pseudoglioma) L homeolog antikoerper, Norrie disease (pseudoglioma) (human) antikoerper, NDP antikoerper, ndp.L antikoerper, Ndp antikoerper
    Hintergrund

    Background: Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.

    Aliases: EVR2 antibody, Exudative vitreoretinopathy 2 (X linked) antibody, FEVR antibody, ND antibody, NDP antibody, NDP_HUMAN antibody, Norrie disease (pseudoglioma) antibody, Norrie disease protein antibody, Norrin antibody, Norrin precursor antibody, X linked exudative vitreoretinopathy 2 protein antibody, X-linked exudative vitreoretinopathy 2 protein antibody

    UniProt
    Q00604
    Pathways
    Sensory Perception of Sound
Sie sind hier: