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NPRL2 Antikörper (AA 1-220)

Dieses Rabbit Polyclonal-Antikörper erkennt spezifisch NPRL2 in WB, ELISA, IHC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7161635

Kurzübersicht für NPRL2 Antikörper (AA 1-220) (ABIN7161635)

Target

Alle NPRL2 Antikörper anzeigen
NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))

Reaktivität

  • 49
  • 32
  • 19
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 47
  • 2
  • 1
Kaninchen

Klonalität

  • 50
Polyklonal

Konjugat

  • 24
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NPRL2 Antikörper ist unkonjugiert

Applikation

  • 42
  • 19
  • 13
  • 13
  • 8
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-220

    Kreuzreaktivität

    Human, Maus

    Aufreinigung

    Antigen Affinity Purified

    Immunogen

    Recombinant Human Nitrogen permease regulator 2-like protein (1-220AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))

    Andere Bezeichnung

    NPRL2

    Hintergrund

    Background: Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at \\\'Tyr-9\\\', \\\'Tyr-373\\\' and \\\'Tyr-376\\\' residues. May act as a tumor suppressor. Suppresses cell growth and enhances sensitivity to various anticancer drugs. As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.

    Aliases: 2810446G01Rik antibody, G21 protein antibody, Gene 21 protein antibody, Homologous to yeast nitrogen permease (candidate tumor suppressor) antibody, Homologous to yeast nitrogen permease antibody, Nitrogen permease regulator 2-like protein antibody, Nitrogen permease regulator-like 2 (S. cerevisiae) antibody, NPR 2L antibody, NPR L2 antibody, NPR like 2 antibody, NPR2 antibody, NPR2 like antibody, NPR2-like protein antibody, NPR2L antibody, NPRL 2 antibody, NPRL2 antibody, NPRL2_HUMAN antibody, Tumor suppressor candidate 4 antibody, TUSC 4 antibody, TUSC 4 protein antibody, TUSC4 antibody, TUSC4 protein antibody

    UniProt

    Q8WTW4
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