NPRL2 Antikörper (AA 1-220)
Kurzübersicht für NPRL2 Antikörper (AA 1-220) (ABIN7161635)
Target
Alle NPRL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- AA 1-220
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                                            Kreuzreaktivität
- Human, Maus
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                                            Aufreinigung
- Antigen Affinity Purified
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                                            Immunogen
- Recombinant Human Nitrogen permease regulator 2-like protein (1-220AA)
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                                            Isotyp
- IgG
 
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                                            Applikationshinweise
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- -20 °C,-80 °C
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                                            Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
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                                            Andere Bezeichnung
- NPRL2
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                                            Hintergrund
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                        Background: Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at \\\'Tyr-9\\\', \\\'Tyr-373\\\' and \\\'Tyr-376\\\' residues. May act as a tumor suppressor. Suppresses cell growth and enhances sensitivity to various anticancer drugs. As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. Aliases: 2810446G01Rik antibody, G21 protein antibody, Gene 21 protein antibody, Homologous to yeast nitrogen permease (candidate tumor suppressor) antibody, Homologous to yeast nitrogen permease antibody, Nitrogen permease regulator 2-like protein antibody, Nitrogen permease regulator-like 2 (S. cerevisiae) antibody, NPR 2L antibody, NPR L2 antibody, NPR like 2 antibody, NPR2 antibody, NPR2 like antibody, NPR2-like protein antibody, NPR2L antibody, NPRL 2 antibody, NPRL2 antibody, NPRL2_HUMAN antibody, Tumor suppressor candidate 4 antibody, TUSC 4 antibody, TUSC 4 protein antibody, TUSC4 antibody, TUSC4 protein antibody 
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                                            UniProt
- Q8WTW4
 Target
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