NrCAM Antikörper (AA 1194-1299) (Biotin)

Produktnummer ABIN7161363

Der Kaninchen Polyklonal Anti-NrCAM-Antikörper wurde für ELISA validiert. Er ist geeignet, NrCAM in Proben von Human zu detektieren.

Kurzübersicht für NrCAM Antikörper (AA 1194-1299) (Biotin) (ABIN7161363)

Target: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NrCAM Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-NrCAM Antikörper (Biotin)

Bindungsspezifität: AA 1194-1299

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Neuronal cell adhesion molecule protein (1194-1299AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NrCAM

Target: NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))

Andere Bezeichnung: NRCAM

Hintergrund:

Background: Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes, not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.

Aliases: Bravo antibody, hBravo antibody, Neuronal cell adhesion molecule antibody, Neuronal surface protein Bravo antibody, Ng CAM related antibody, Ng-CAM-related antibody, NgCAM related cell adhesion molecule antibody, NgCAM-related cell adhesion molecule antibody, Nr CAM antibody, Nr-CAM antibody, Nrcam antibody, NRCAM_HUMAN antibody

UniProt: Q92823

Pathways: Regulation of Cell Size