UNC5D Antikörper (AA 90-212) (Biotin)

Produktnummer ABIN7161188

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch UNC5D in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für UNC5D Antikörper (AA 90-212) (Biotin) (ABIN7161188)

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC5D Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-UNC5D Antikörper (Biotin)

Bindungsspezifität: AA 90-212

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Netrin receptor UNC5D protein (90-212AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu UNC5D

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Andere Bezeichnung: UNC5D

Hintergrund:

Background: Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity). Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity). May play a role in apoptosis in response to DNA damage (PubMed:24691657). It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed:24519068). Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity).

Aliases: UNC5D antibody, KIAA1777 antibody, UNC5H4 antibody, UNQ6012/PRO34692 antibody, Netrin receptor UNC5D antibody, Protein unc-5 homolog 4 antibody, Protein unc-5 homolog D antibody

UniProt: Q6UXZ4