PDZK1 Antikörper (AA 1-519) (HRP)

Produktnummer ABIN7160812

Dieses Anti-PDZK1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PDZK1 in ELISA. Geeignet für Human.

Kurzübersicht für PDZK1 Antikörper (AA 1-519) (HRP) (ABIN7160812)

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDZK1 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-PDZK1 Antikörper (HRP)

Bindungsspezifität: AA 1-519

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Na(+)/H(+) exchange regulatory cofactor NHE-RF3 protein (1-519AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PDZK1

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Andere Bezeichnung: PDZK1

Hintergrund:

Background: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function

Aliases: 1700023D20Rik antibody, 2610507N21Rik antibody, 4921513F16Rik antibody, AI267131 antibody, AI314638 antibody, AL022680 antibody, C terminal linking and modulating protein antibody, CAP70 antibody, CFTR associated protein of 70 kDa antibody, CFTR associated protein, 70-KD antibody, CFTR-associated protein of 70 kDa antibody, CLAMP antibody, D3Ertd537e antibody, Dietary Pi-regulated RNA-1 antibody, Diphor-1 antibody, mPDZK1 antibody, Na(+)/H(+) exchange regulatory cofactor NHE-RF3 antibody, Na(+)/H(+) exchanger regulatory factor 3 antibody, Na/Pi cotransporter C-terminal-associated protein 1 antibody, Na/Pi cotransporter C-terminal-associated protein antibody, NaPi Cap1 antibody, NaPi-Cap1 antibody, NaPiCap1 antibody, NHERF 3 antibody, NHERF-3 antibody, NHERF3 antibody, NHRF3_HUMAN antibody, OTTHUMP00000015572 antibody, PDZ domain containing 1 antibody, PDZ domain containing protein 1 antibody, PDZ domain-containing protein 1 antibody, PDZD1 antibody, PDZK1 antibody, Sodium hydrogen exchanger regulatory factor 3 antibody, Sodium-hydrogen exchanger regulatory factor 3 antibody

UniProt: Q5T2W1