SGSH Antikörper (AA 273-502)

Produktnummer ABIN7160782

Dieses Anti-SGSH-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SGSH in IHC und ELISA. Geeignet für Human.

Kurzübersicht für SGSH Antikörper (AA 273-502) (ABIN7160782)

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGSH Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-SGSH Antikörper

Bindungsspezifität: AA 273-502

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human N-sulphoglucosamine sulphohydrolase protein (273-502AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SGSH

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Andere Bezeichnung: SGSH

Hintergrund:

Background: SGSH(N-sulphoglucosamine sulphohydrolase) is also named as HSS, sulphamidase and belongs to the sulfatase family. Sulfamidase is synthesized as a 62 kDa precursor protein, which is modified with mannose 6-phosphate (M6P) residues, allowing their recognition by mannose-6-phosphate receptors in the Golgi complex and ensuring transport to the endosomal/lysosomal system. It catalyzes the third step of degradation of glucosaminoglycans and is required for the degradation of heparan sulphate. Defects in SGSH are the cause of mucopolysaccharidosis type 3A (MPS3A), also known as Sanfilippo syndrome A.

Aliases: Heparan sulfate sulfatase antibody, Heparan sulphate sulphatase antibody, HSS antibody, MPS 3A antibody, MPS3 A antibody, MPS3A antibody, Mucopolysaccharidosis type IIIA antibody, N sulfoglucosamine sulfohydrolase (sulfamidase) antibody, N sulfoglucosamine sulfohydrolase antibody, N-sulphoglucosamine sulphohydrolase antibody, SFMD antibody, SGSH antibody, SPHM_HUMAN antibody, Sulfoglucosamine sulfamidase antibody, Sulphamidase antibody, Sulphoglucosamine sulphamidase antibody

UniProt: P51688

Pathways: Glycosaminoglycan Metabolic Process