SMYD2A Antikörper (AA 115-272)

Produktnummer ABIN7160774

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMYD2A in ELISA, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SMYD2A Antikörper (AA 115-272) (ABIN7160774)

Target: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMYD2A Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SMYD2A Antikörper

Bindungsspezifität: AA 115-272

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human N-lysine methyltransferase SMYD2 protein (115-272AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SMYD2A

Target: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Andere Bezeichnung: SMYD2

Hintergrund:

Background: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 \\\'Lys-4\\\' (H3K4me) and dimethylates histone H3 \\\'Lys-36\\\' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates \\\'Lys-370\\\' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at \\\'Lys-860\\\'.

Aliases: Histone methyltransferase SMYD2 antibody, HSKM B antibody, HSKM-B antibody, HSKMB antibody, KMT3C antibody, Lysine N-methyltransferase 3C antibody, MGC119305 antibody, N lysine methyltransferase SMYD2 antibody, N-lysine methyltransferase SMYD2 antibody, SET and MYND domain containing 2 antibody, SET and MYND domain containing protein 2 antibody, SET and MYND domain-containing protein 2 antibody, Smyd2 antibody, SMYD2_HUMAN antibody, Zinc finger MYND domain containing 14 antibody, ZMYND14 antibody

UniProt: Q9NRG4