DMPK Antikörper (AA 243-424) (FITC)

Produktnummer ABIN7160625

Der Kaninchen Polyklonal Anti-DMPK-Antikörper wurde für validiert. Er ist geeignet, DMPK in Proben von Human zu detektieren.

Kurzübersicht für DMPK Antikörper (AA 243-424) (FITC) (ABIN7160625)

Target: DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMPK Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-DMPK Antikörper (FITC)

Bindungsspezifität: AA 243-424

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Myotonin-protein kinase protein (243-424AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DMPK

Target: DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

Andere Bezeichnung: DMPK

Hintergrund:

Background: Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeostasis. Phosphorylates PLN, a regulator of calcium pumps and may regulate sarcoplasmic reticulum calcium uptake in myocytes. May also phosphorylate FXYD1/PLM which is able to induce chloride currents. May also play a role in synaptic plasticity.

Aliases: DM 1 antibody, DM antibody, DM kinase antibody, DM protein kinase antibody, DM-kinase antibody, DM1 antibody, DM1 protein kinase antibody, DM1PK antibody, DMK antibody, DMPK antibody, DMPK_HUMAN antibody, Dystrophia myotonica 1 antibody, Dystrophia myotonica protein kinase antibody, MDPK antibody, MT PK antibody, MT-PK antibody, Myotonic dystrophy associated protein kinase antibody, Myotonic dystrophy protein kinase antibody, Myotonin protein kinase A antibody, Myotonin protein kinase antibody, Myotonin-protein kinase antibody, Thymopoietin homolog antibody

UniProt: Q09013

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development