MPZL1 Antikörper (AA 195-258)

Produktnummer ABIN7160421

Produktdetails anti-MPZL1 Antikörper

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Bindungsspezifität: AA 195-258

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPZL1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Myelin protein zero-like protein 1 protein (195-258AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MPZL1

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Andere Bezeichnung: MPZL1 (MPZL1 Produkte)

Synonyme: MPZL1 antikoerper, MPZL1b antikoerper, PZR antikoerper, PZR1b antikoerper, PZRa antikoerper, PZRb antikoerper, 1110007A10Rik antikoerper, myelin protein zero like 1 antikoerper, myelin protein zero-like 1 antikoerper, MPZL1 antikoerper, Mpzl1 antikoerper

Hintergrund:

Background: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Aliases: MPZL1 antibody, PZR antibody, UNQ849/PRO1787 antibody, Myelin protein zero-like protein 1 antibody, Protein zero-related antibody

UniProt: O95297