MUC1 Antikörper (AA 24-273)

Produktnummer ABIN7160277

Der Kaninchen Polyklonal Anti-MUC1-Antikörper wurde für IHC, ELISA und IF validiert. Er ist geeignet, MUC1 in Proben von Human zu detektieren.

Kurzübersicht für MUC1 Antikörper (AA 24-273) (ABIN7160277)

Target: MUC1 (Mucin 1 (MUC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-MUC1 Antikörper

Bindungsspezifität: AA 24-273

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Mucin-1 protein (24-273AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MUC1

Target: MUC1 (Mucin 1 (MUC1))

Andere Bezeichnung: MUC1

Hintergrund:

Background: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. Ref.26 Ref.37 Ref.40 Ref.45 Ref.46 Ref.49 Ref.52 Ref.53 Ref.56.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

Aliases: ADMCKD antibody, ADMCKD1 antibody, Breast carcinoma associated antigen DF3 antibody, Breast carcinoma-associated antigen DF3 antibody, CA 15-3 antibody, CA15 3 antibody, CA15 3 antigen antibody, CA15-3 antibody, CA15.3 antibody, Cancer antigen 15-3 antibody, Carcinoma associated mucin antibody, Carcinoma-associated mucin antibody, CD 227 antibody, CD227 antibody, DF3 antigen antibody, EMA antibody, Episialin antibody, Epithelial Membrane Antigen antibody, H23 antigen antibody, H23AG antibody, KL 6 antibody, KL-6 antibody, KL6 antibody, Krebs von den Lungen-6 antibody, MAM 6 antibody, MAM6 antibody, MCD antibody, MCKD antibody, MCKD1 antibody, Medullary cystic kidney disease 1 (autosomal dominant) antibody, Medullary cystic kidney disease, autosomal dominant antibody, MUC 1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1 antibody, MUC1-alpha antibody, MUC1-beta antibody, MUC1-CT antibody, MUC1-NT antibody, MUC1/ZD antibody, MUC1_HUMAN antibody, Mucin 1 antibody, Mucin 1 cell surface associated antibody, Mucin 1 transmembrane antibody, Mucin 1, cell surface associated antibody, Mucin-1 subunit beta antibody, Peanut reactive urinary mucin antibody, Peanut-reactive urinary mucin antibody, PEM antibody, PEMT antibody, Polymorphic epithelial mucin antibody, PUM antibody, Tumor associated epithelial membrane antigen antibody, Tumor associated epithelial mucin antibody, Tumor associated mucin antibody, Tumor-associated epithelial membrane antigen antibody, Tumor-associated mucin antibody

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling