MAP3K9 Antikörper (AA 864-1098) (Biotin)

Produktnummer ABIN7160062

Dieses Anti-MAP3K9-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MAP3K9 in ELISA. Geeignet für Human.

Kurzübersicht für MAP3K9 Antikörper (AA 864-1098) (Biotin) (ABIN7160062)

Target: MAP3K9 (Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K9 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-MAP3K9 Antikörper (Biotin)

Bindungsspezifität: AA 864-1098

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Mitogen-activated protein kinase kinase kinase 9 protein (864-1098AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MAP3K9

Target: MAP3K9 (Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9))

Andere Bezeichnung: MAP3K9

Hintergrund:

Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.

Aliases: M3K9_HUMAN antibody, Map3k9 antibody, MEKK9 antibody, Mitogen activated protein kinase kinase kinase 9 antibody, Mitogen-activated protein kinase kinase kinase 9 antibody, Mixed lineage kinase 1 (tyr and ser/thr specificity) antibody, Mixed lineage kinase 1 antibody, MLK1 antibody, PRKE1 antibody

UniProt: P80192