C20orf72 Antikörper (AA 81-260)

Produktnummer ABIN7159874

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch C20orf72 in ELISA, WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für C20orf72 Antikörper (AA 81-260) (ABIN7159874)

Target: C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C20orf72 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-C20orf72 Antikörper

Bindungsspezifität: AA 81-260

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Mitochondrial genome maintenance exonuclease 1 protein (81-260AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu C20orf72

Target: C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))

Andere Bezeichnung: MGME1

Hintergrund:

Background: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5\'-3\' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.

Aliases: MGME1 antibody, C20orf72 antibody, DDK1Mitochondrial genome maintenance exonuclease 1 antibody, EC 3.1.-.- antibody

UniProt: Q9BQP7