MACF1 Antikörper (AA 1936-2150) (FITC)

Produktnummer ABIN7159744

Dieses Anti-MACF1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MACF1 in . Geeignet für Human.

Kurzübersicht für MACF1 Antikörper (AA 1936-2150) (FITC) (ABIN7159744)

Target: MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MACF1 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-MACF1 Antikörper (FITC)

Bindungsspezifität: AA 1936-2150

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 protein (1936-2150AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MACF1

Target: MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))

Andere Bezeichnung: MACF1

Hintergrund:

Background: Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells (By similarity).

Aliases: MACF1 antibody, ABP620 antibody, ACF7 antibody, KIAA0465 antibody, KIAA1251 antibody, Microtubule-actin cross-linking factor 1 antibody, isoforms 1/2/3/5 antibody, 620 kDa actin-binding protein antibody, ABP620 antibody, Actin cross-linking family protein 7 antibody, Macrophin-1 antibody, Trabeculin-alpha antibody

UniProt: Q9UPN3