APOO Antikörper (AA 26-198)

Produktnummer ABIN7159688

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch APOO in IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für APOO Antikörper (AA 26-198) (ABIN7159688)

Target: APOO (Apolipoprotein O (APOO))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOO Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-APOO Antikörper

Bindungsspezifität: AA 26-198

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human MICOS complex subunit MIC26 protein (26-198AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu APOO

Target: APOO (Apolipoprotein O (APOO))

Andere Bezeichnung: APOO

Hintergrund:

Background: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:25764979). Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts (PubMed:24743151). Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL (PubMed:16956892).

Aliases: 0610008C08Rik antibody, 1110019O03Rik antibody, Apolipoprotein O antibody, APOO antibody, APOO_HUMAN antibody, FAM121B antibody, Family with sequence similarity 121B antibody, MGC130105 antibody, MGC130106 antibody, MGC4825 antibody, My025 antibody, MYO25 antibody, OTTHUMP00000023073 antibody, Protein FAM121B antibody, RP23-272D10.2 antibody

UniProt: Q9BUR5