STEAP1 Antikörper (AA 3-69)

Produktnummer ABIN7159501

Dieses Anti-STEAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von STEAP1 in WB, ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für STEAP1 Antikörper (AA 3-69) (ABIN7159501)

Target: STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-STEAP1 Antikörper

Bindungsspezifität: AA 3-69

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Metalloreductase STEAP1 protein (3-69AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu STEAP1

Target: STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))

Andere Bezeichnung: STEAP1

Hintergrund:

Background: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis By similarity. Mediates \\\'Lys-63\\\'-linked polyubiquitination of TBK1, which probably participates in kinase activation.

Aliases: 2410007B19Rik antibody, EC 1.16.1.- antibody, Metalloreductase STEAP1 antibody, MGC19484 antibody, PRSS 24 antibody, PRSS24 antibody, Six transmembrane epithelial antigen of prostate antibody, Six transmembrane epithelial antigen of the prostate 1 antibody, Six transmembrane epithelial antigen of the prostate antibody, Six-transmembrane epithelial antigen of prostate 1 antibody, STEA1_HUMAN antibody, STEAP 1 antibody, Steap antibody, STEAP1 antibody

UniProt: Q9UHE8

Pathways: Transition Metal Ion Homeostasis