Meprin B Antikörper (AA 480-652)

Produktnummer ABIN7159412

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Meprin B in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Meprin B Antikörper (AA 480-652) (ABIN7159412)

Target: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Meprin B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Meprin B Antikörper

Bindungsspezifität: AA 480-652

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Meprin A subunit beta protein (480-652AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Meprin B

Target: Meprin B (MEP1B) (Meprin A, beta (MEP1B))

Andere Bezeichnung: MEP1B

Hintergrund:

Background: Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1\\\' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.

Aliases: Endopeptidase 2 antibody, Endopeptidase-2 antibody, kinase splitting membranal proteinase antibody, KSMP antibody, Mep1b antibody, MEP1B_HUMAN antibody, Meprin 1 beta subunit antibody, Meprin A beta antibody, Meprin A beta subunit precursor antibody, Meprin A subunit beta antibody, Meprin B antibody, N benzoyl L tyrosyl P amino benzoic acid hydrolase beta subunit antibody, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta antibody, PABA peptide hydrolase antibody, PPH beta antibody

UniProt: Q16820