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PKC theta Antikörper (pSer676) (Biotin)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PKC theta in WB, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN711718

Kurzübersicht für PKC theta Antikörper (pSer676) (Biotin) (ABIN711718)

Target

Alle PKC theta (PRKCQ) Antikörper anzeigen
PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

Reaktivität

  • 97
  • 70
  • 56
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 123
  • 3
  • 1
  • 1
Kaninchen

Klonalität

  • 122
  • 6
Polyklonal

Konjugat

  • 68
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser PKC theta Antikörper ist konjugiert mit Biotin

Applikation

  • 112
  • 47
  • 41
  • 40
  • 40
  • 20
  • 13
  • 9
  • 6
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 28
    • 27
    • 15
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer676

    Homologie

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human PRKCQ around the phosphorylation site of Ser676

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

    Andere Bezeichnung

    PRKCQ

    Hintergrund

    Synonyms: PRKCQphospho S676, PKCSer676, PKC thetaphospho S676, PKC 0, PRKCQ, PKC0, Prkcq, PRKCT, Protein kinase C theta, Protein kinase C theta type, Protein Kinase Ctheta, KPCT_HUMAN, nPKC theta, nPKC-theta, nPKCtheta.

    Background: This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

    Gen-ID

    5588

    Pathways

    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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