MAML1 Antikörper (AA 1-45)
Kurzübersicht für MAML1 Antikörper (AA 1-45) (ABIN7159033)
Target
Alle MAML1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-45
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Mastermind-like protein 1 protein (1-45AA)
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Isotyp
- IgG
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anti-Mastermind-Like 1 (MAML1) (N-Term) antibody
MAML1 Reaktivität: Human, Maus WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 198-225) antibodyMAML1 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB18757 unconjugated
anti-Mastermind-Like 1 (MAML1) (N-Term) antibodyVerified MAML1 Reaktivität: Human ELISA, WB, IHC Wirt: Ziege Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 655-754) antibodyMAML1 Reaktivität: Human ELISA, WB Wirt: Maus Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 1-300) antibodyMAML1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 205-234), (Middle Region) antibodyMAML1 Reaktivität: Human WB, FACS, EIA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MAML1 (Mastermind-Like 1 (MAML1))
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Andere Bezeichnung
- MAML1
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Hintergrund
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Background: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
Aliases: Mam-1 antibody, Mam1 antibody, MAML 1 antibody, Maml1 antibody, MAML1_HUMAN antibody, Mastermind like 1 antibody, Mastermind-like protein 1 antibody
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UniProt
- Q92585
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Pathways
- Notch Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
-
