MRGPRX2 Antikörper (AA 286-330) (Biotin)

Produktnummer ABIN7159014

Der Kaninchen Polyklonal Anti-MRGPRX2-Antikörper wurde für ELISA validiert. Er ist geeignet, MRGPRX2 in Proben von Human zu detektieren.

Kurzübersicht für MRGPRX2 Antikörper (AA 286-330) (Biotin) (ABIN7159014)

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRGPRX2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-MRGPRX2 Antikörper (Biotin)

Bindungsspezifität: AA 286-330

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Mas-related G-protein coupled receptor member X2 protein (286-330AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MRGPRX2

Target: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Andere Bezeichnung: MRGPRX2

Hintergrund:

Background: Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.

Aliases: G protein coupled receptor MRGX 2 antibody, G protein coupled receptor MRGX2 antibody, Mas related G protein coupled receptor member X2 antibody, Mas related gene MRGX 2 antibody, Mas related gene MRGX2 antibody, MAS related GPR member X2 antibody, Mas-related G-protein coupled receptor member X antibody, Mas-related G-protein coupled receptor member X2 antibody, MRGPRX 2 antibody, MRGPRX2 antibody, MRGX 2 antibody, MRGX2 antibody, MRGX2_HUMAN antibody

UniProt: Q96LB1