SLC27A1 Antikörper (AA 453-570)

Produktnummer ABIN7158492

Der Kaninchen Polyklonal Anti-SLC27A1-Antikörper wurde für ELISA und IF validiert. Er ist geeignet, SLC27A1 in Proben von Human zu detektieren.

Kurzübersicht für SLC27A1 Antikörper (AA 453-570) (ABIN7158492)

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC27A1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-SLC27A1 Antikörper

Bindungsspezifität: AA 453-570

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Long-chain fatty acid transport protein 1 protein (453-570AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SLC27A1

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Andere Bezeichnung: SLC27A1

Hintergrund:

Background: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (By similarity).

Aliases: SLC27A1 antibody, ACSVL5 antibody, FATP1Long-chain fatty acid transport protein 1 antibody, FATP-1 antibody, Fatty acid transport protein 1 antibody, EC 6.2.1.- antibody, Solute carrier family 27 member 1 antibody

UniProt: Q6PCB7

Pathways: Inositol Metabolic Process, Regulation of Lipid Metabolism by PPARalpha