LONP1 Antikörper (AA 614-959) (Biotin)

Produktnummer ABIN7158489

Der Kaninchen Polyklonal Anti-LONP1-Antikörper wurde für ELISA validiert. Er ist geeignet, LONP1 in Proben von Human zu detektieren.

Kurzübersicht für LONP1 Antikörper (AA 614-959) (Biotin) (ABIN7158489)

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LONP1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-LONP1 Antikörper (Biotin)

Bindungsspezifität: AA 614-959

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Lon protease homolog, mitochondrial protein (614-959AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu LONP1

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Andere Bezeichnung: LONP1

Hintergrund:

Background: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.

Aliases: hLON antibody, hLON ATP dependent protease antibody, LON antibody, lon peptidase 1, mitochondrial antibody, LON protease antibody, Lon protease homolog antibody, Lon protease like protein antibody, Lon protease-like protein antibody, LONHs antibody, LONM_HUMAN antibody, LONP antibody, Lonp1 antibody, MGC1498 antibody, mitochondrial antibody, Mitochondrial ATP dependent protease Lon antibody, Mitochondrial ATP-dependent protease Lon antibody, Mitochondrial lon peptidase 1 antibody, PIM1 antibody, Protease serine 15 antibody, PRSS15 antibody, Serine protease 15 antibody

UniProt: P36776