FLRT3 Antikörper (AA 209-264) (FITC)

Produktnummer ABIN7158124

Dieses Anti-FLRT3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FLRT3 in . Geeignet für Human.

Kurzübersicht für FLRT3 Antikörper (AA 209-264) (FITC) (ABIN7158124)

Target: FLRT3 (Fibronectin Leucine Rich Transmembrane Protein 3 (FLRT3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLRT3 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-FLRT3 Antikörper (FITC)

Bindungsspezifität: AA 209-264

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Leucine-rich repeat transmembrane protein FLRT3 protein (209-264AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FLRT3

Target: FLRT3 (Fibronectin Leucine Rich Transmembrane Protein 3 (FLRT3))

Andere Bezeichnung: FLRT3

Hintergrund:

Background: Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:26235030). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (By similarity). Promotes neurite outgrowth (in vitro) (PubMed:14706654). Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length. Plays a role in the regulation of the density of glutamaergic synapses. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning. Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development. Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (By similarity).

Aliases: fibronectin leucine rich transmembrane protein 3 antibody, Fibronectin-like domain-containing leucine-rich transmembrane protein 3 antibody, FLRT 3 antibody, FLRT3 antibody, FLRT3_HUMAN antibody, KIAA1469 antibody, Leucine-rich repeat transmembrane protein FLRT3 antibody

UniProt: Q9NZU0