KSR2 Antikörper (AA 159-296) (FITC)
Kurzübersicht für KSR2 Antikörper (AA 159-296) (FITC) (ABIN7157560)
Target
Alle KSR2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 159-296
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Kinase suppressor of Ras 2 protein (159-296AA)
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Isotyp
- IgG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KSR2 (Kinase Suppressor of Ras 2 (KSR2))
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Andere Bezeichnung
- KSR2
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Hintergrund
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Background: Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
Aliases: FLJ25965 antibody, hKSR 2 antibody, hKSR2 antibody, Kinase suppressor of Ras 2 antibody, KSR 2 antibody, Ksr2 antibody, KSR2_HUMAN antibody
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UniProt
- Q6VAB6
Target
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