JUP Antikörper (AA 1-131)

Produktnummer ABIN7157158

Dieses Anti-JUP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von JUP in WB, IHC und ELISA. Geeignet für Human.

Kurzübersicht für JUP Antikörper (AA 1-131) (ABIN7157158)

Target: JUP (Junction Plakoglobin (JUP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JUP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-JUP Antikörper

Bindungsspezifität: AA 1-131

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Junction plakoglobin protein (1-131AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu JUP

Target: JUP (Junction Plakoglobin (JUP))

Andere Bezeichnung: JUP

Hintergrund:

Background: Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).

Aliases: ARVD 12 antibody, ARVD12 antibody, Catenin (cadherin associated protein), gamma 80 kDa antibody, catenin (cadherin-associated protein) gamma (80kD) antibody, Catenin gamma antibody, CTNNG antibody, Desmoplakin 3 antibody, Desmoplakin III antibody, Desmoplakin-3 antibody, Desmoplakin3 antibody, DesmoplakinIII antibody, DP 3 antibody, DP III antibody, DP3 antibody, DPIII antibody, gamma catenin antibody, Junction plakoglobin antibody, JUP antibody, OTTHUMP00000164732 antibody, OTTHUMP00000164735 antibody, OTTHUMP00000164738 antibody, PDGB antibody, PKGB antibody, PLAK_HUMAN antibody, PLAKOGLOBIN antibody

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location