IST1 Antikörper (AA 172-284) (Biotin)

Produktnummer ABIN7157139

Der Kaninchen Polyklonal Anti-IST1-Antikörper wurde für ELISA validiert. Er ist geeignet, IST1 in Proben von Human zu detektieren.

Kurzübersicht für IST1 Antikörper (AA 172-284) (Biotin) (ABIN7157139)

Target: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IST1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-IST1 Antikörper (Biotin)

Bindungsspezifität: AA 172-284

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human IST1 homolog protein (172-284AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IST1

Target: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Andere Bezeichnung: IST1

Hintergrund:

Background: ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (PubMed:19129479, PubMed:19129480). During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing (PubMed:26040712). Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST (PubMed:23897888).

Aliases: hIST1 antibody, Increased sodium tolerance 1 antibody, Increased sodium tolerance 1 homolog antibody, IST1 homolog antibody, IST1_HUMAN antibody, KIAA0174 antibody, MAPK activating protein PM28 antibody, MGC117220 antibody, MGC128433 antibody, Putative MAPK-activating protein PM28 antibody

UniProt: P53990

Pathways: Regulation of Cell Size