IREB2 Antikörper (AA 107-216) (HRP)

Produktnummer ABIN7157049

Der Kaninchen Polyklonal Anti-IREB2-Antikörper wurde für ELISA validiert. Er ist geeignet, IREB2 in Proben von Human zu detektieren.

Kurzübersicht für IREB2 Antikörper (AA 107-216) (HRP) (ABIN7157049)

Target: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IREB2 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-IREB2 Antikörper (HRP)

Bindungsspezifität: AA 107-216

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Iron-responsive element-binding protein 2 protein (107-216AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IREB2

Target: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Andere Bezeichnung: IREB2

Hintergrund:

Background: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5\'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3\'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Aliases: ACO3 antibody, FLJ23381 antibody, IRE BP2 antibody, IRE-BP 2 antibody, IREB 2 antibody, IREB2 antibody, IREB2_HUMAN antibody, Iron regulatory protein 2 antibody, iron responsive element binding protein 2 antibody, Iron-responsive element-binding protein 2 antibody, IRP 2 antibody, IRP2 antibody, IRP2AD antibody, OTTHUMP00000185022 antibody

UniProt: P48200

Pathways: Transition Metal Ion Homeostasis