IL1F9 Antikörper (AA 1-169)

Produktnummer ABIN7156905

Der Kaninchen Polyklonal Anti-IL1F9-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, IL1F9 in Proben von Human zu detektieren.

Kurzübersicht für IL1F9 Antikörper (AA 1-169) (ABIN7156905)

Target: IL1F9 (Interleukin 1 Family Member 9 (IL1F9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1F9 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-IL1F9 Antikörper

Bindungsspezifität: AA 1-169

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Interleukin-36 gamma protein (1-169AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IL1F9

Target: IL1F9 (Interleukin 1 Family Member 9 (IL1F9))

Andere Bezeichnung: IL36G

Hintergrund:

Background: Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response, similar to the IL-1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. In cultured keratinocytes induces the expression of macrophage, T-cell, and neutrophil chemokines, such as CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CL20, CCL5, CCL2, CCL17, CCL22, CXCL8, CCL20 and CXCL1, also stimulates its own expression and that of the prototypic cutaneous proinflammatory parameters TNF-alpha, S100A7/psoriasin and inducible NOS. May play a role in proinflammatory responses during particular neutrophilic airway inflammation: activates mitogen-activated protein kinases and NF-kappa B in primary lung fibroblasts, and stimulates the expression of IL-8 and CXCL3 and Th17 chemokine CCL20 in lung fibroblasts. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus.

Aliases: IL 1 epsilon antibody, IL 1 related protein 2 antibody, IL 1(EPSILON) antibody, IL 1F9 antibody, IL 1H1 antibody, IL 1RP2 antibody, IL-1 epsilon antibody, IL-1-related protein 2 antibody, IL-1F9 antibody, IL-1H1 antibody, IL-1RP2 antibody, IL1E antibody, Il1f9 antibody, IL1F9_HUMAN antibody, IL1H1 antibody, IL1RP2 antibody, IL36 gamma antibody, IL36G antibody, Interleukin 1 epsilon antibody, Interleukin 1 family member 9 antibody, Interleukin 1 homolog 1 antibody, Interleukin 1 related protein 2 antibody, Interleukin 36 gamma antibody, Interleukin-1 epsilon antibody, Interleukin-1 family member 9 antibody, Interleukin-1 homolog 1 antibody

UniProt: Q9NZH8