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Integrin beta 7 Antikörper (AA 1-140)

Dieses Anti-Integrin beta 7-Antikörper ist ein Rabbit Polyclonal-Antikörper zur Detektion von Integrin beta 7 in WB, ELISA, IHC. Geeignet für Human.
Produktnummer ABIN7156498

Kurzübersicht für Integrin beta 7 Antikörper (AA 1-140) (ABIN7156498)

Target

Alle Integrin beta 7 (ITGB7) Antikörper anzeigen
Integrin beta 7 (ITGB7)

Reaktivität

  • 77
  • 31
  • 1
  • 1
  • 1
Human

Wirt

  • 50
  • 20
  • 7
  • 4
  • 1
Kaninchen

Klonalität

  • 51
  • 29
  • 2
Polyklonal

Konjugat

  • 36
  • 8
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Integrin beta 7 Antikörper ist unkonjugiert

Applikation

  • 40
  • 28
  • 21
  • 13
  • 13
  • 8
  • 8
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 9
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-140

    Kreuzreaktivität

    Human

    Aufreinigung

    Antigen Affinity Purified

    Immunogen

    Recombinant Human Integrin beta-7 protein (1-140AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    Integrin beta 7 (ITGB7)

    Andere Bezeichnung

    ITGB7

    Hintergrund

    Background: Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.

    Aliases: Gut homing receptor beta subunit antibody, Integrin beta 7 subunit antibody, Integrin beta-7 antibody, Integrin beta-P antibody, Integrin, beta 7 antibody, ITB7 antibody, ITB7_HUMAN antibody, Itgb7 antibody, Ly69 antibody, M290 IEL antigen antibody

    UniProt

    P26010

    Pathways

    Integrin Complex
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