IVNS1ABP Antikörper (AA 401-642)

Produktnummer ABIN7156223

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IVNS1ABP in IHC, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IVNS1ABP Antikörper (AA 401-642) (ABIN7156223)

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IVNS1ABP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-IVNS1ABP Antikörper

Bindungsspezifität: AA 401-642

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Influenza virus NS1A-binding protein (401-642AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IVNS1ABP

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Andere Bezeichnung: IVNS1ABP

Substanzklasse: Influenza Protein

Hintergrund:

Background: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization, Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing, may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.

Aliases: IVNS1ABP antibody, ARA3 antibody, FLARA3 antibody, KIAA0850 antibody, KLHL39 antibody, NS1 antibody, NS1BP antibody, HSPC068 antibody, Influenza virus NS1A-binding protein antibody, NS1-BP antibody, NS1-binding protein antibody, Aryl hydrocarbon receptor-associated protein 3 antibody, Kelch-like protein 39 antibody

UniProt: Q9Y6Y0

Pathways: Negative Regulation of intrinsic apoptotic Signaling