Importin 11 Antikörper (AA 1-270) (Biotin)

Produktnummer ABIN7156139

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Importin 11 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Importin 11 Antikörper (AA 1-270) (Biotin) (ABIN7156139)

Target: Importin 11 (IPO11)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Importin 11 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-Importin 11 Antikörper (Biotin)

Bindungsspezifität: AA 1-270

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Importin-11 protein (1-270AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Importin 11

Target: Importin 11 (IPO11)

Andere Bezeichnung: IPO11

Hintergrund:

Background: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).

Aliases: Imp11 antibody, Importin 11 antibody, Importin-11 antibody, IPO11 antibody, IPO11_HUMAN antibody, Ran binding protein 11 antibody, Ran-binding protein 11 antibody, RanBP11 antibody, SLRN antibody, Synleurin antibody

UniProt: Q9UI26

Pathways: Protein targeting to Nucleus