HIP1 Antikörper (AA 410-690)
Kurzübersicht für HIP1 Antikörper (AA 410-690) (ABIN7155937)
Target
Alle HIP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 410-690
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity purified
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Immunogen
- Recombinant Human Huntingtin-interacting protein 1 protein (410-690AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HIP1 (Huntingtin Interacting Protein 1 (HIP1))
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Andere Bezeichnung
- HIP1
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Hintergrund
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Background: Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors.
Aliases: 2610109B09Rik antibody, A930014B11Rik antibody, E130315I21Rik antibody, HIP 1 antibody, HIP I antibody, HIP-1 antibody, HIP-I antibody, hip1 antibody, HIP1/PDGFRB fusion gene antibody, HIP1/PDGFRB fusion gene, included antibody, HIP1_HUMAN antibody, HIPI antibody, Huntingtin interacting protein 1 antibody, Huntingtin Interacting Protein HIP1 antibody, Huntingtin-interacting protein 1 antibody, Huntingtin-interacting protein I antibody, ILWEQ antibody, KIAA4113 antibody, MGC126506 antibody, MGC27616 antibody, mKIAA4113 antibody
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UniProt
- O00291
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Pathways
- Positive Regulation of Endopeptidase Activity
Target
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