HCFC1 Antikörper (AA 201-428)

Produktnummer ABIN7155909

Der Kaninchen Polyklonal Anti-HCFC1-Antikörper wurde für IHC, ELISA und IF validiert. Er ist geeignet, HCFC1 in Proben von Human zu detektieren.

Kurzübersicht für HCFC1 Antikörper (AA 201-428) (ABIN7155909)

Target: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCFC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-HCFC1 Antikörper

Bindungsspezifität: AA 201-428

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Host cell factor 1 protein (201-428AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HCFC1

Target: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Andere Bezeichnung: HCFC1

Hintergrund:

Background: Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2, represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. Tethers the chromatin modifying Set1/Ash2 histone H3 \\\'Lys-4\\\' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. In case of human herpes simplex virus (HSV) infection, HCFC1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and POU2F1 thereby enabling the transcription of the viral immediate early genes.

Aliases: C1 factor antibody, CFF antibody, HCF 1 antibody, HCF antibody, HCF C-terminal chain 6 antibody, HCF-1 antibody, HCF1 antibody, Hcfc1 antibody, HCFC1_HUMAN antibody, HFC1 antibody, Host cell factor 1 antibody, Host cell factor antibody, Host cell factor C1 (VP16 accessory protein) antibody, Host cell factor C1 antibody, MGC70925 antibody, MRX3 antibody, VCAF antibody, VP16 accessory protein antibody

UniProt: P51610