HIPK1 Antikörper (AA 1007-1151) (Biotin)

Produktnummer ABIN7155862

Dieses Anti-HIPK1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HIPK1 in ELISA. Geeignet für Human.

Kurzübersicht für HIPK1 Antikörper (AA 1007-1151) (Biotin) (ABIN7155862)

Target: HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIPK1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-HIPK1 Antikörper (Biotin)

Bindungsspezifität: AA 1007-1151

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Homeodomain-interacting protein kinase 1 protein (1007-1151AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HIPK1

Target: HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))

Andere Bezeichnung: HIPK1

Hintergrund:

Background: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.

Aliases: Hipk 1 antibody, Hipk1 antibody, HIPK1_HUMAN antibody, Homeodomain interacting protein kinase 1 antibody, Homeodomain interacting protein kinase 1 like protein antibody, Homeodomain-interacting protein kinase 1 antibody, Myak antibody, Nbak 2 antibody, Nbak2 antibody, Nuclear body associated kinase 2 antibody, Nuclear body associated kinase 2b antibody

UniProt: Q86Z02