MEOX1 Antikörper (AA 1-254)

Produktnummer ABIN7155798

Der Kaninchen Polyklonal Anti-MEOX1-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, MEOX1 in Proben von Human zu detektieren.

Kurzübersicht für MEOX1 Antikörper (AA 1-254) (ABIN7155798)

Target: MEOX1 (Mesenchyme Homeobox 1 (MEOX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEOX1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-MEOX1 Antikörper

Bindungsspezifität: AA 1-254

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Homeobox protein MOX-1 protein (1-254AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MEOX1

Target: MEOX1 (Mesenchyme Homeobox 1 (MEOX1))

Andere Bezeichnung: MEOX1

Hintergrund:

Background: Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.

Aliases: Homeobox protein MOX-1 antibody, MEOX1 antibody, MEOX1_HUMAN antibody, Mesenchyme homeo box 1 antibody, Mesenchyme homeobox 1 antibody, MOX 1 antibody, MOX1 antibody

UniProt: P50221

Pathways: Chromatin Binding