PAK6 Antikörper (pSer165) (FITC)

Produktnummer ABIN711318

Dieses Anti-PAK6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PAK6 in WB, IF (cc) und IF (p). Geeignet für Human und Maus.

Kurzübersicht für PAK6 Antikörper (pSer165) (FITC) (ABIN711318)

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK6 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PAK6 Antikörper (FITC)

Bindungsspezifität: pSer165

Kreuzreaktivität: Human, Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human PAK6 around the phosphorylation site of Ser165

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PAK6

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Andere Bezeichnung: PAK6

Hintergrund:

Synonyms: PAK6phospho S165, CDKN1A activated kinase 6, p21 activated protein kinase 6, p21 protein Cdc42/Rac-activated kinase 6, p21CDKN1A activated kinase 6, p21-ACTIVATED KINASE 6, p21activated kinase 6, PAK 5, PAK 6, PAK5, Serine threonine protein kinase PAK 6, Serine/threonine protein kinase PAK 6, Serine/threonine protein kinase PAK6.

Background: This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.

Gen-ID: 56924