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H2AFB1 Antikörper (AA 1-115)

H2AFB1 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7155373
  • Target Alle H2AFB1 Antikörper anzeigen
    H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))
    Bindungsspezifität
    • 4
    • 1
    • 1
    AA 1-115
    Reaktivität
    Human
    Wirt
    • 6
    Kaninchen
    Klonalität
    • 6
    Polyklonal
    Konjugat
    • 2
    • 2
    • 1
    • 1
    Dieser H2AFB1 Antikörper ist unkonjugiert
    Applikation
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Histone H2A-Bbd type 1 protein (1-115AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    H2AFB1 (H2A Histone Family, Member B1 (H2AFB1))
    Andere Bezeichnung
    H2AFB1 (H2AFB1 Produkte)
    Synonyme
    H2A.Bbd antikoerper, H2A histone family member B1 antikoerper, H2AFB1 antikoerper
    Hintergrund

    Background: Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis.

    Aliases: H2AB1 antibody, H2AFB1 antibody, Histone H2A-Bbd type 1 antibody, H2A Barr body-deficient antibody, H2A.B antibody, H2A.Bbd antibody

    UniProt
    P0C5Y9
    Pathways
    Telomere Maintenance
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