HDAC7 Antikörper (AA 647-917) (Biotin)

Produktnummer ABIN7155324

Der Kaninchen Polyklonal Anti-HDAC7-Antikörper wurde für ELISA validiert. Er ist geeignet, HDAC7 in Proben von Human zu detektieren.

Kurzübersicht für HDAC7 Antikörper (AA 647-917) (Biotin) (ABIN7155324)

Target: HDAC7 (Histone Deacetylase 7 (HDAC7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC7 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-HDAC7 Antikörper (Biotin)

Bindungsspezifität: AA 647-917

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Histone deacetylase 7 protein (647-917AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HDAC7

Target: HDAC7 (Histone Deacetylase 7 (HDAC7))

Andere Bezeichnung: HDAC7

Hintergrund:

Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).

Aliases: DKFZP586J0917 antibody, FLJ99588 antibody, HD 7a antibody, HD7 antibody, HD7a antibody, HDAC 7 antibody, HDAC 7A antibody, Hdac7 antibody, HDAC7_HUMAN antibody, HDAC7A antibody, Histone deacetylase 7 antibody, Histone deacetylase 7A antibody, OTTHUMP00000202813 antibody, OTTHUMP00000202814 antibody

UniProt: Q8WUI4

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development