KAT5 Antikörper (AA 3-512)

Produktnummer ABIN7155274

Dieses Anti-KAT5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KAT5 in WB, ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für KAT5 Antikörper (AA 3-512) (ABIN7155274)

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KAT5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-KAT5 Antikörper

Bindungsspezifität: AA 3-512

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Histone acetyltransferase KAT5 protein (3-512AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KAT5

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Andere Bezeichnung: KAT5

Hintergrund:

Background: Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.

Aliases: 60 kDa Tat interactive protein antibody, 60 kDa Tat-interactive protein antibody, cPLA(2) interacting protein antibody, cPLA(2)-interacting protein antibody, cPLA2 antibody, cPLA2 interacting protein antibody, ESA1 antibody, Histone acetyltransferase HTATIP antibody, Histone acetyltransferase KAT5 antibody, HIV 1 Tat interactive protein antibody, HIV 1 Tat interactive protein, 60 kDa antibody, HIV-1 Tat interactive protein antibody, HTATIP antibody, HTATIP1 antibody, K(lysine) acetyltransferase 5 antibody, K-acetyltransferase 5 antibody, KAT5 antibody, KAT5_HUMAN antibody, Lysine acetyltransferase 5 antibody, PLIP antibody, Tat interacting protein, 60 kDa antibody, TIP antibody, Tip60 antibody

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway