HMGB3 Antikörper (AA 1-103) (HRP)

Produktnummer ABIN7155216

Der Kaninchen Polyklonal Anti-HMGB3-Antikörper wurde für ELISA validiert. Er ist geeignet, HMGB3 in Proben von Human zu detektieren.

Kurzübersicht für HMGB3 Antikörper (AA 1-103) (HRP) (ABIN7155216)

Target: HMGB3 (High Mobility Group Box 3 (HMGB3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGB3 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-HMGB3 Antikörper (HRP)

Bindungsspezifität: AA 1-103

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human High mobility group protein B3 protein (1-103AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HMGB3

Target: HMGB3 (High Mobility Group Box 3 (HMGB3))

Andere Bezeichnung: HMGB3

Hintergrund:

Background: Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).

Aliases: chromosomal protein, Nonhistone, HMG4 antibody, High mobility group (nonhistone chromosomal) protein 4 antibody, High mobility group box 3 antibody, High mobility group protein 2a antibody, High mobility group protein 4 antibody, High mobility group protein B3 antibody, High mobility group protein HMG4 antibody, HMG 4 antibody, HMG-2a antibody, HMG-4 antibody, HMG2A antibody, HMGB 3 antibody, Hmgb3 antibody, HMGB3_HUMAN antibody, MGC90319 antibody, Non histone chromosomal protein antibody, Nonhistone chromosomal protein HMG4 antibody

UniProt: O15347