RAN Antikörper (AA 1-216)

Produktnummer ABIN7154577

Der Kaninchen Polyklonal Anti-RAN-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, RAN in Proben von Human zu detektieren.

Kurzübersicht für RAN Antikörper (AA 1-216) (ABIN7154577)

Target: RAN (RAN, Member RAS Oncogene Family (RAN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-RAN Antikörper

Bindungsspezifität: AA 1-216

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human GTP-binding nuclear protein Ran protein (1-216AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RAN

Target: RAN (RAN, Member RAS Oncogene Family (RAN))

Andere Bezeichnung: RAN

Hintergrund:

Background: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.

Aliases: Androgen receptor associated protein 24 antibody, Androgen receptor-associated protein 24 antibody, ARA 24 antibody, ARA24 antibody, Gsp1 antibody, GTP binding nuclear protein RAN antibody, GTP-binding nuclear protein Ran antibody, GTPase Ran antibody, Guanosine triphosphatase Ran antibody, LPS antibody, OK/SW-cl.81 antibody, ran antibody, RAN member RAS oncogene family antibody, RAN_HUMAN antibody, RanGTPase antibody, Ras like protein TC4 antibody, Ras related nuclear protein antibody, Ras-like protein TC4 antibody, Ras-related nuclear protein antibody, RASL2 8 antibody, TC 4 antibody, TC4 antibody

UniProt: P62826

Pathways: Regulatorische RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus