GDF5 Antikörper (AA 202-501)

Produktnummer ABIN7154549

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GDF5 in WB, IHC, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GDF5 Antikörper (AA 202-501) (ABIN7154549)

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-GDF5 Antikörper

Bindungsspezifität: AA 202-501

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Growth/differentiation factor 5 protein (202-501AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GDF5

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Andere Bezeichnung: GDF5

Hintergrund:

Background: Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (By similarity). Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

Aliases: BMP14 antibody, Cartilage derived morphogenetic protein 1 antibody, Cartilage-derived morphogenetic protein 1 antibody, CDMP-1 antibody, CDMP1 antibody, GDF-5 antibody, Gdf5 antibody, GDF5_HUMAN antibody, Growth differentiation factor 5 antibody, Growth/differentiation factor 5 antibody, LAP4 antibody, OS5 antibody, Radotermin antibody, SYNS2 antibody

UniProt: P43026