GRHL1 Antikörper (AA 1-95) (Biotin)

Produktnummer ABIN7154373

Der Kaninchen Polyklonal Anti-GRHL1-Antikörper wurde für ELISA validiert. Er ist geeignet, GRHL1 in Proben von Human zu detektieren.

Kurzübersicht für GRHL1 Antikörper (AA 1-95) (Biotin) (ABIN7154373)

Target: GRHL1 (Grainyhead-Like 1 (GRHL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRHL1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-GRHL1 Antikörper (Biotin)

Bindungsspezifität: AA 1-95

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Grainyhead-like protein 1 homologprotein (1-95AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GRHL1

Target: GRHL1 (Grainyhead-Like 1 (GRHL1))

Andere Bezeichnung: GRHL1

Hintergrund:

Background: Transcription factor involved in epithelial development. Binds directly to the consensus DNA sequence 5\'-AACCGGTT-3\' (PubMed:12175488, PubMed:18288204). Important regulator of DSG1 in the context of hair anchorage and epidermal differentiation, participates in the maintenance of the skin barrier. There is no genetic interaction with GRHL3, no functional cooperativity due to diverse target gene selectivity during epithelia development (By similarity). Isoform 1 may function as an activator and isoform 2 as a repressor in tissues where both forms are expressed (PubMed:12175488).

Aliases: Grainyhead-like protein 1 homolog antibody, grhl1 antibody, GRHL1_HUMAN antibody, LBP32 antibody, Mammalian grainyhead antibody, MGR antibody, NH32 antibody, TFCP2L2 antibody, Transcription factor CP2-like 2 antibody, Transcription factor LBP-32 antibody

UniProt: Q9NZI5

Pathways: Regulation of Lipid Metabolism by PPARalpha