GS28 Antikörper (AA 1-115)

Produktnummer ABIN7154311

Dieses Anti-GS28-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GS28 in ELISA und IHC. Geeignet für Human.

Kurzübersicht für GS28 Antikörper (AA 1-115) (ABIN7154311)

Target: GS28 (GOSR1) (Golgi SNAP Receptor Complex Member 1 (GOSR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GS28 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-GS28 Antikörper

Bindungsspezifität: AA 1-115

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Golgi SNAP receptor complex member 1 protein (1-115AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GS28

Target: GS28 (GOSR1) (Golgi SNAP Receptor Complex Member 1 (GOSR1))

Andere Bezeichnung: GOSR1

Hintergrund:

Background: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.

Aliases: GOSR1 antibody, GS28Golgi SNAP receptor complex member 1 antibody, 28 kDa Golgi SNARE protein antibody, 28 kDa cis-Golgi SNARE p28 antibody, GOS-28 antibody

UniProt: O95249