GPC1 Antikörper (AA 342-530) (Biotin)

Produktnummer ABIN7154265

Der Kaninchen Polyklonal Anti-GPC1-Antikörper wurde für ELISA validiert. Er ist geeignet, GPC1 in Proben von Human zu detektieren.

Kurzübersicht für GPC1 Antikörper (AA 342-530) (Biotin) (ABIN7154265)

Target: GPC1 (Glypican 1 (GPC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPC1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-GPC1 Antikörper (Biotin)

Bindungsspezifität: AA 342-530

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Glypican-1 protein (342-530AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GPC1

Target: GPC1 (Glypican 1 (GPC1))

Andere Bezeichnung: GPC1

Hintergrund:

Background: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

Aliases: FLJ38078 antibody, glypican antibody, Glypican proteoglycan 1 antibody, glypican1 antibody, GPC 1 antibody, Gpc1 antibody, GPC1_HUMAN antibody, Secreted glypican-1 antibody

UniProt: P35052

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation