GGT1 Antikörper (AA 13-225)

Produktnummer ABIN7154060

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GGT1 in ELISA, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GGT1 Antikörper (AA 13-225) (ABIN7154060)

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GGT1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-GGT1 Antikörper

Bindungsspezifität: AA 13-225

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Glutathione hydrolase 1 proenzyme protein (13-225AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GGT1

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Andere Bezeichnung: GGT1

Hintergrund:

Background: Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.

Aliases: CD224 antibody, D22S672 antibody, D22S732 antibody, Gamma glutamyl transpeptidase antibody, Gamma glutamyltransferase 1 antibody, Gamma glutamyltranspeptidase 1 antibody, Gamma-glutamyltransferase 1 antibody, Gamma-glutamyltranspeptidase 1 light chain antibody, GGT 1 antibody, GGT antibody, GGT1 antibody, GGT1_HUMAN antibody, Glutamyl transpeptidase antibody, Glutathione hydrolase 1 antibody, GTG antibody, Leukotriene C4 hydrolase antibody, MGC96892 antibody, MGC96904 antibody, MGC96963 antibody, OTTHUMP00000028921 antibody, OTTHUMP00000197959 antibody

UniProt: P19440