POFUT2 Antikörper (AA 125-271) (Biotin)

Produktnummer ABIN7153730

Dieses Rabbit Polyclonal-Antikörper erkennt spezifisch POFUT2 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für POFUT2 Antikörper (AA 125-271) (Biotin) (ABIN7153730)

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POFUT2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-POFUT2 Antikörper (Biotin)

Bindungsspezifität: AA 125-271

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human GDP-fucose protein O-fucosyltransferase 2 protein (125-271AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu POFUT2

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Andere Bezeichnung: POFUT2

Hintergrund:

Background: Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm (By similarity). Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13.

Aliases: POFUT2 antibody, C21orf80 antibody, FUT13 antibody, KIAA0958 antibody, GDP-fucose protein O-fucosyltransferase 2 antibody, EC 2.4.1.221 antibody, Peptide-O-fucosyltransferase 2 antibody, O-FucT-2 antibody

UniProt: Q9Y2G5