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Gasdermin A Antikörper (AA 64-172) (FITC)

GSDMA Reaktivität: Human Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN7153649
  • Target Alle Gasdermin A (GSDMA) Antikörper anzeigen
    Gasdermin A (GSDMA)
    Bindungsspezifität
    • 15
    • 14
    • 7
    • 3
    • 1
    • 1
    AA 64-172
    Reaktivität
    • 34
    • 25
    • 16
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 35
    Kaninchen
    Klonalität
    • 35
    Polyklonal
    Konjugat
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Gasdermin A Antikörper ist konjugiert mit FITC
    Applikation
    Bitte anfragen
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Gasdermin-A protein (64-172AA)
    Isotyp
    IgG
    Top Product
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  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Gasdermin A (GSDMA)
    Andere Bezeichnung
    GSDMA (GSDMA Produkte)
    Synonyme
    BB149167 antikoerper, Gsdm antikoerper, Gsdm1 antikoerper, Gsdma1 antikoerper, H312E antikoerper, GSDM1 antikoerper, GSDM antikoerper, gasdermin A antikoerper, Gsdma antikoerper, GSDMA antikoerper
    Hintergrund

    Background: May promote pyroptosis (Probable). Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity (PubMed:27281216). The physiological relevance of these observations is unknown (Probable).

    Aliases: GSDMA antibody, GSDM antibody, GSDM1 antibody, FKSG9Gasdermin-A antibody, Gasdermin-1 antibody

    UniProt
    Q96QA5
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